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Sunday 13 December 2020

Making of Human

 

Development of the human body is the process of growth to maturity. The process begins with fertilization, where an egg released from the ovary of a female is penetrated by a sperm cell from a male. The resulting zygote develops through mitosis and cell differentiation, and the resulting embryo then implants in the uterus, where the embryo continues development through a fetal stage until birth.


                                     Germinal Stage

 The germinal stage refers to the time from fertilization through the development of the early embryo until implantation is completed in the uterus. The germinal stage takes around 10 days. During this stage, the zygote begins to divide, in a process called cleavage. A blastocyst is then formed and implanted in the uterus. Embryonic development continues with the next stage of gastrulation, when the three germ layers of the embryo form in a process called histogenesis, and the processes of neurulation and organogenesis follow.

 

 Blastocyst Development

Blastocyst development is important stage for the formation of organs in embryo. The blastocyst stays inside a protective cover during maturation called zona pellucida, which could be described as an egg shell. The outer cells are located right below this cover, which will create the future placenta and surrounding tissues to support fetal development in the uterus. The inner cells of the blastocyst will become the different tissues and organs of the human body, such as bones, muscles, skin, liver, and heart.

 Embryo Development

As the blastocyst reaches the final steps in the implantation process into the inner lining of the uterus, it evolves into a structure called an embryo. This is the time when internal organs and external structures develop. The mouth, lower jaw, throat are emerging, while the blood circulation system starts its evolution and a heart tube is created. The ears arise and arms, legs, fingers, toes, and eyes are being shaped. The brain and the spinal cord are already formed, while the digestive tract and sensory organs start their development. The first bones are replacing the cartilage.

After ten-twelve weeks of pregnancy, the embryo moves into the final stage of development, a fetus.

Gastrulation

Gastrulation starts in the 3rd week, the inner cell or embryo starts differentiating into three germinal layers, i.e. ectoderm, endoderm and mesoderm. These cells transform and get differentiated to all the tissues and organs, like nerve, blood, muscle, bone, digestive tract, etc.

Ectoderm- nervous system, brain, spinal cord, epidermis, hair, nails, etc.

Mesoderm- connective tissue, muscles, circulatory system, notochord, bone, kidney, gonads

Endoderm- internal organs, stomach, liver, pancreas, bladder, lung, gut lining

 Fetal Development

By the twelfth week of fertilization the embryo moves into the final stage of development called the fetal stage. By now, the fetus has formed all of the organs and structures necessary for a baby, but those organs still need to grow and develop.

At three months of pregnancy, the upper and lower extremities of the fetus are completely developed. Ears and teeth are formed and the reproductive organs have evolved. At the end of this month, the fetus has completed the expansion of most of the circulatory and urinary systems and its length is about 5 inches.

At six months, the fetus can respond to sounds and is around 12 inches long. The fetus continues to develop and grow changing position and responding to sounds, and stimuli. The length of the little body can reach 14 inches.

The fetus becomes a baby at month eight. The brain is evolving quickly so the baby can see and hear, although the respiratory system requires maturation. The baby can weigh approximately 5 pounds. Close to the end of the pregnancy at month 9, the baby responds to stimuli, can move the whole body but space around the new human being is becoming too tight.

     

                                   


                                         PLACENTA

The interdigitated chronic villi of trophoblast and uterine cells form the placenta, which is the connection between the mother and the growing foetus.

The placenta provides nourishment and oxygen to the embryo and helps in removing carbon dioxide and waste produced by the embryo. It also acts as an endocrine gland and secretes various hormones like hCG (Human Chorionic Gonadotropin), estrogen, progestogens, etc. for maintenance of pregnancy.


                               Formation of Human Organ

1.The heart is the first functional organ to develop and starts to beat and pump blood at around 22 days.

2.The digestive system starts to develop from the third week and by the twelfth week, the organs have correctly positioned themselves.

3. The respiratory system develops from the lung bud, which appears in the ventral wall of the foregut about four weeks into development.

4. Brain developed around eight week

5. After12 week Male and female external genital differences observable

 Stages of Growth Month-by-Month in Pregnancy

First trimester

The first trimester will span from conception to 12 weeks. This is generally the first three months of pregnancy. During this trimester, your baby will change from a small grouping of cells to a fetus that is starting to have a baby’s features.

Second trimester

This middle section of pregnancy is often thought of as the best part of the experience. By this time, any morning sickness is probably gone and the discomfort of early pregnancy has faded. The baby will start to develop facial features during this month. You may also start to feel movement as your baby flips and turns in the uterus. During this trimester, many people find out the sex of the baby. This is typically done during an anatomy scan (an ultrasound that checks your baby’s physical development) around 20 weeks.

Third trimester

This is the final part of your pregnancy. You may be tempted to start the countdown till your due date and hope that it would come early, but each week of this final stage of development helps your baby prepare for childbirth. Throughout the third trimester, your baby will gain weight quickly, adding body fat that will help after birth.

  

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